Repeatedly getting hit by poison-based attacks will apply the "Poison" status abnormality. Guarding such attacks does not prevent Poison from accumulating.

Poison affects the body and mind when it enters the body, gradually reducing Vitality over time.

Poison is a Status Abnormality in Sekiro: Shadows Die Twice. The Poisoned effect can afflict both enemies and the player character, dealing damage to hitpoints over time.



How to Cure Poison

Players can cure Poison by using the Antidote Powder item.

Sekiro might obtain the Poison status if he is hit by multiple poisoned attacks. Enemies with Poison attacks include (but are not limited to):

  • Senpou Assassin/Rats (short, stocky wooden-hat enemies from Ashina)
  • Poisonous Lizard
  • Certain bosses
  • Poisonous pools in Ashina Depths 



How to Inflict Poison

  • Sekiro can use the Sabimaru Prosthetic tool  to stack up poison. Note that enemies weak to Poison will take huge Posture Damage and will be staggered when afflicted with the Poisoned Status.



Enemies Weak to Poison



Enemies Resistant to Poison

Those who live in Poisonous areas have very high resistance to the "Poison" status abnormality. Some are even completely immune to it.

  • Snake Eyes Shirafuji is highly resistant to poison, making the Sabimaru impractical against her. However, she is not completely immune and can be poisoned if she is lured into the surrounding poison pit for long enough.
  • Example



Status Abnormalities
Burn  ♦  Enfeebled  ♦  Shock  ♦  Terror

    • Anonymous

      01 May 2019 18:01  

      I don't know about the peoples around Gunfort area, even after the 1.03 patch. Don't get me wrong, Shirafuji is very weak to poison, no question about it but I tested Sabimaru on the big fatties, those who're using the large guns that shoots fragmented bullets (the only one worth using Sabimaru on, to be honest) and even after a couple full combos they were still not poisoned. Nothing compared to Okami warriors who gets destroyed by it after taking a few hits (you don't even have to finish a single combo). Those seems very much weak to poison to me, the peoples around Gunfort area, not so much.

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